Suikoden VI is a tough subject: there are so many potentialities and variables that it is really hard to have any vision for what it could be. As far as platform, I'd like to see it on home consoles, that is where the series belongs in my opinion. Though, in many ways I see a potential SVI as something of an avatar to right the wrongs of the whole games industry.
I think a lot of us feel that way, even if we don't know it. Games are beginning to lose interest for me, not because I am older now and "growing out of them," but because of the changes to the basic design philosophies that many games are based on. They are becoming more influenced by cinema and less by literature and the fairy tale. More visceral and dark, and less whimsical and imaginative. I can go back and play many older games and still be captured like before, but newer games are becoming less tolerable. Some are good, even great, but it feels like you have to slog through a swamp of dross just to find even one.
So, less important than 2D or 3D, or any other consideration, is that the game would understand the design and writing philosophy of the originals, and how they work as a counter-point to the rest of the industry today. This might be difficult, as most of the literary-trained writers have fled or been pushed out of the industry, or have been so hamstrung by their bosses that even the most talented wouldn't be able to stand out. Everything else is just of lesser importance to me, I suppose.
Ominous Latinus Phraseus